1.  Known effectiveness of Cranial Electrotherapy Stimulation (CES) in mental health.¹
   1. Anxiety:  38 clinical studies of anxiety, 21 of which were double blind, showed a mean improvement of 58%, with a range of from 38% to 94% improvement.
   2. Depression:  18 clinical studies of depression, 7 of which were double blind, showed a mean improvement of 47%, with a range of from 25% to 80% improvement.
   3. Insomnia: 19 clinical studies of insomnia, 7 of which were double blind showed a mean improvement of 62%, with a range of from 37% to 93% improvement.
   4. Cognitive Dysfunction: 13 studies of cognitive dysfunction of various kinds, 54% of which were single or double blind, showed a mean improvement of 44%, with a range of from 23% to 86% improvement.

Note: These patients were treated with CES for 45 to 60 minutes a day for 10 to 14 days.  They continued to improve for the next 6 weeks once treatment had been discontinued.  All of this treatment was medication free, though CES can be used in the presence of medication, and appears to potentiate medication.

1. Theoretical impact of CES in PTSD treatment.
   1. PTSD is caused by traumatic memories coming to the fore unbidden, which disrupt the person’s personality and behavior while active.
   2. Eliciting the traumatic memory(s) during therapy is necessary but can be a difficult and long drawn out process because the memory can trigger the PTSD response and defeat therapy.
   3. CES can prevent the emotional response to traumatic memory while the current is on.²
   4. Recalled memories can be deleted from the brain within 3 to 10 minutes from the time they are called up, and other memories inserted if the patient remains calm and does not go into the PTSD response, thus ending the PTSD.³

Note:  Perhaps the greatest problem of PTSD therapists is the amount of time required to enable the patient to recall the traumatic experience in therapy without triggering a full blown anxiety response.  That could be prevented if CES were worn by the patient while the traumatic event was recalled.  At that point the memory could be removed from the memory stores and/or replaced by a less traumatic version of the memory.

References:

1. Smith, Ray B. (2007) Cranial electrotherapy stimulation; Its first fifty years, plus three: A monograph. Tate: Mustang, OK.
2. Smith, R.B., and F.N. Shiromoto (1992) The use of cranial electrotherapy stimulation to block fear perception in phobic patients. Current Therapeutic Research, 51(2):249-253.
3. Shiller, D. Marie-H. Monfils, Candace M. Raio, David C. Johnson, Joseph E. LeDoux, Elizabeth A Phelps (2009) Preventing the return of fear in humans using reconsolidation update mechanisms. Nature, published online 9 December, 2009.