In the last decade of the 20th century, several well controlled, double blind studies sought to discover what, if anything CES treatment could do to alleviate the sometimes intractable pain of fibromyalgia. It was found that Patients given CES treatment reported the same reduction in tender point pain and self-rated overall pain level that they reported when treated with multiple medications, but without any of the negative side effects or great financial outlay.
Another study found a 29% reduction in the pain of patients suffering from multiple sclerosis following four weeks of daily CES treatment. Serendipitously, it was also found that they experienced a 40% reduction in their fatigue score, a 45% reduction in self-reported sensory deficits, a 50% reduction in their MS related vision problems and a 53% reduction in problems with spasticity.
Other studies have found CES clinically effective in reducing pain in spinal chord injury patients, in patients suffering from full body reflex sympathetic dystrophy, and in general dentistry.